British Pharmacopoeia Chemical reference substances (BPCRS)

These Primary standards are established using absolute methods and the declared content figures are determined without comparing to another substance. You should use BPCRS to perform the tests in the British Pharmacopoeia (BP) or BP (Veterinary). Do not eat BPCRS or feed them to animals – you should only use BPCRS for chemical analysis. They are not suitable for any other use.

30/06/2025

Dear valued customer,

We are writing to let you know that, due to an electrical fault, our freezers in which some BPCRS vial stock was stored switched off for a short period and the storage temperature may have been compromised over the weekend of 21st/22nd June. This was detected promptly and rectified, but as a precaution we have removed all affected items from sale and are conducting thorough testing to verify their stability and usability.

Consequently, you may notice in the short term that a higher number of products than usual are showing as “out of stock”. This process is necessary to ensure that only products that meet our quality standards are shipped to you.

We sincerely apologise for any inconvenience and appreciate your patience and understanding, and would like to reassure you that;

· None of the affected vials have been shipped to customers.

· All affected vials have been quarantined.

· We are urgently reviewing the material stability data and carrying out testing to determine if the material has been affected.

· We have additional bulk supplies of the materials which have not been affected and we can produce more vials from these bulks.

Products will be brought back into stock as soon as we can confirm they have not been affected. As we assess the products and gather more data we will be able to update with estimated timeframes in due course. As soon as we have further information we will update this page.

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  • Search result 1

    Category Number 1093
    Pack size 125 mg
    Substance name irbesartan
    Declared content
    99.7% of C25H28N6O
    Current batch 3461
    QTY (Max 25)
  • Search result 2

    Category Number 1122
    Pack size 10 mg
    Substance name irbesartan impurity A
    Declared content Not applicable
    Current batch 3676
    QTY (Max 25)
  • Search result 3

    Category Number 550
    Pack size 100 mg
    Substance name isoconazole nitrate
    Declared content
    99.7% of C18H14Cl4N2O,HNO3
    Current batch 2139
    Discontinued
  • Search result 4

    Category Number 1083
    Pack size 100 mg
    Substance name isoniazid
    Declared content
    99.7% of C6H7N3O
    Current batch 3400
    QTY (Max 25)
  • Search result 5

    Category Number 205
    Pack size 100 mg
    Substance name isoprenaline hydrochloride
    Declared content
    99.6% of C11H17NO3HCl
    Current batch 3889
    QTY (Max 25)
  • Search result 6

    Category Number 778
    Pack size 25 mg
    Substance name isopromethazine hydrochloride
    Declared content Not applicable
    Current batch 4441
    QTY (Max 25)
  • Search result 7

    Category Number 799
    Pack size 15 mg
    Substance name isosorbide 2-nitrate
    Declared content Not applicable
    Current batch 4880
    QTY (Max 2)
  • Search result 8

    Category Number 206
    Pack size 300 mg
    Substance name isosorbide dinitrate
    Declared content
    39.9% of C6H8N2O8
    Current batch 4416
    E-mail to order:  bpcrs@mhra.gov.uk
  • Search result 9

    Category Number 800
    Pack size 100 mg
    Substance name isosorbide mononitrate
    Declared content
    99.9% of C6H9NO6
    Current batch 4088
    Out of Stock
  • Search result 10

    Category Number 621
    Pack size 100 mg
    Substance name isradipine
    Declared content
    99.6% of C19H21N3O5
    Current batch 2166
    Discontinued
  • Search result 11

    Category Number 622
    Pack size 25 mg
    Substance name isradipine impurity B
    Declared content Not applicable
    Current batch 2167
    Discontinued
  • Search result 12

    Category Number 624
    Pack size 25 mg
    Substance name isradipine impurity D
    Declared content Not applicable
    Current batch 2168
    Discontinued
  • Search result 13

    Category Number 1199
    Pack size 100 mg
    Substance name itraconazole
    Declared content
    99.7% of C35H38CI2N8O4
    Current batch 3947
    QTY (Max 25)
  • Search result 14

    Category Number 864
    Pack size 250 mg
    Substance name ivermectin
    Declared content
    87.6% of C48H74O14 (ivermectin H2B1a) 3.5% of C47H72O14 (ivermectin H2B1b)
    Current batch 3020
    QTY (Max 2)
  • Search result 15

    Category Number 861
    Pack size 50 mg
    Substance name kanamycin monosulfate
    Declared content Not applicable
    Current batch 3005
    QTY (Max 25)
  • Search result 16

    Category Number 736
    Pack size 100 mg
    Substance name ketamine hydrochloride
    Declared content
    86.5% of C13H16ClNO (for HPLC)
    86.5% of C13H16ClNO (for UV)
    Current batch 4077
    QTY (Max 5)
  • Search result 17

    Category Number 1169
    Pack size 100 mg
    Substance name ketoconazole
    Declared content
    100.0% of C26H28CI2N4O4
    Current batch 3788
    QTY (Max 25)
  • Search result 18

    Category Number 1170
    Pack size 25 mg
    Substance name ketoconazole impurity standard
    Declared content Not applicable
    Current batch 4591
    QTY (Max 10)
  • Search result 19

    Category Number 668
    Pack size 100 mg
    Substance name ketoprofen
    Declared content
    99.9 % of C16H14O3
    Current batch 3982
    QTY (Max 25)
  • Search result 20

    Category Number 667
    Pack size 100 mg
    Substance name ketoprofen ethyl ester
    Declared content Not applicable
    Current batch 4706
    Out of Stock